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Rifabutin concentration in serum/plasma (quantitative measurement)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of rifabutin, an antibiotic used to treat certain infections, in your blood.

Quick summary

["Knowing your rifabutin level helps doctors monitor your dose for safe and effective treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25199-1
Short code
Rifabutin Islt Slgr Mcbct AB 1.0
Synonyms
Rifabutin Islt Slgr Mcbct AB 1.0
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria-antibiotic-concentration-at-ug-ml
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking rifabutin to treat conditions like tuberculosis or other infections. It helps ensure the medication is working properly and at the right dose for you.

What to Expect Before the Test

No special preparation is needed. You’ll likely have a small needle inserted into your arm or hand to draw a blood sample. The process is quick and usually painless.

What the Results Mean

Results help your doctor check if your rifabutin levels are within the target range for your treatment. Too little may mean the drug isn’t working, while too much could cause side effects.

Common Side Effects to Watch For

While rare, rifabutin can cause side effects like nausea, stomach pain, or skin rash. If you notice unusual symptoms, contact your doctor right away.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Rifabutin levels are critical for preventing resistance to the drug and ensuring it remains effective against infections. Low levels may require dose adjustments, while high levels could lead to toxicity or drug interactions.

Short name

Rifabutin Level

Frequently asked questions

Why is my rifabutin level checked regularly?
Regular checks help your doctor adjust your dose to keep it safe and effective, especially if you’re taking other medications that could affect rifabutin levels.
What happens if my rifabutin level is too low?
If levels are too low, your doctor may increase your dose or switch to a different medication to ensure you get the full benefits of rifabutin.
Can I drink alcohol while taking rifabutin?
It’s best to avoid alcohol while on rifabutin, as it may increase side effects or interfere with how the drug works in your body.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy