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Protein Electrophoresis, Serum (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood serum using gel electrophoresis, a method that separates proteins based on size and charge.

Quick summary

["Understanding your protein profile can help identify abnormalities in blood protein composition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72317-1
Short code
RNAp III RP11 IgG SerPl Ql IA
Synonyms
RNAp III RP11 IgG SerPl Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Electrophoresis separates proteins into distinct bands corresponding to albumin, alpha-globulins, beta-globulins, and gamma-globulins. This qualitative test provides a visual profile of these protein fractions, which can help detect conditions like multiple myeloma, liver disease, or other protein disorders.

Why Might You Need This Test?

Your healthcare provider may order this test to investigate symptoms such as unexplained weight loss, fatigue, swelling, or changes in kidney/liver function. It’s also used to monitor certain chronic conditions or screen for inherited protein disorders.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The serum portion (liquid after clotting) is then analyzed in a lab to separate proteins by size and charge.

Common Uses and Conditions

This test is often used to diagnose or monitor conditions like multiple myeloma, Waldenström macroglobulinemia, liver disease, kidney disease, or hereditary protein disorders (e.g., alpha-1 antitrypsin deficiency).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Protein Electrophoresis

Frequently asked questions

How long will it take to get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your healthcare provider is recommended to discuss findings.
Can I eat or drink before this test?
No special diet is required, but avoid alcohol for 24 hours before testing to ensure accurate results. Fasted samples may be preferred in some cases, but confirm with your provider.
What if my results are abnormal?
Abnormal results may indicate an underlying condition requiring further testing or evaluation by your doctor. They may recommend additional blood tests, imaging, or other diagnostic procedures to determine the cause.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy