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Serum/plasma concentration of rosiglitazone (a thiazolidinedione antidiabetic medication)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of rosiglitazone in your blood, which helps your doctor check if your medication is working as intended and if it’s at a safe level for you.

Quick summary

["This test helps monitor your rosiglitazone dose and side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73158-8
Short code
Rosiglitazone ind plt IgM SerPl Ql FC
Synonyms
Rosiglitazone ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking rosiglitazone (Avandia) to manage type 2 diabetes. It helps ensure the medication is effective and helps detect potential issues like low blood sugar or drug interactions.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually from a vein in your arm, by a healthcare professional.

What the Results Mean

Results show the concentration of rosiglitazone in your blood. High levels may indicate overdose or improper metabolism, while low levels could mean the medication isn’t working as expected. Your doctor will interpret these results in the context of your overall health and treatment plan.

Common Causes of Abnormal Results

Abnormal results may occur if you’ve missed doses, taken extra medication, or have liver or kidney issues that affect how your body processes rosiglitazone.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High rosiglitazone levels may increase the risk of side effects like fluid retention, heart risks, or liver problems. Low levels may suggest inadequate diabetes control. Regular monitoring helps balance effectiveness and safety.

Short name

ROSIGLITAZONE LEVEL

Frequently asked questions

When might I need this test?
This test is typically done periodically if you’re on rosiglitazone to check for safe dosing and effectiveness, especially if you have kidney or liver conditions or take other medications that interact with it.
What does a ‘normal’ result mean?
There’s no single ‘normal’ range for rosiglitazone because it varies based on dose, metabolism, and individual health. Your doctor will use the result to guide your treatment plan.
Can I eat or drink before this test?
You can eat and drink normally unless your doctor specifies otherwise, as blood tests for medication levels usually don’t require fasting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy