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Rosuvastatin-Induced Platelet IgG, Serum/Plasma — Qualitative, Flow Cytometry

Published: August 9, 2026Updated: August 17, 2026

Detects IgG antibodies that bind to platelets in the presence of rosuvastatin, which can help evaluate suspected immune-mediated thrombocytopenia.

Quick summary

["A positive result supports rosuvastatin-induced immune thrombocytopenia, especially when low platelets develop after starting the drug."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
73157-0
Short code
Rosuvastatin ind plt IgG SerPl Ql FC
Synonyms
Rosuvastatin ind plt IgG SerPl Ql FC
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test looks for IgG antibodies that attach to platelets when rosuvastatin is present. These drug-dependent antibodies can cause the immune system to destroy platelets, leading to a low platelet count.

Why might I need this test?

It may be ordered if your platelet count is low or you have bruising, bleeding, or other symptoms after starting rosuvastatin. The result helps determine whether rosuvastatin may be contributing to immune-mediated thrombocytopenia.

How is the test performed?

A blood sample is collected and separated into serum or plasma. The laboratory uses flow cytometry to determine whether patient IgG binds to platelets in the presence of rosuvastatin.

How do I prepare for the test?

No special preparation is usually needed. Tell your clinician when you started rosuvastatin and when symptoms or low platelet counts began, and do not stop or change the medication without medical advice.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates that rosuvastatin-dependent platelet IgG is present and supports a diagnosis of drug-induced immune thrombocytopenia. A negative result does not completely exclude the condition, so results must be interpreted with the medication timeline, platelet count, symptoms, and other possible causes.

Short name

Rosuvastatin platelet antibody test

Frequently asked questions

What does a positive result mean?
It means the blood contains IgG antibodies that bind to platelets in the presence of rosuvastatin. This supports the possibility that rosuvastatin is triggering immune destruction of platelets.
Can this test determine how severe my thrombocytopenia is?
No. The platelet count and your clinical findings determine the severity and urgency of low platelets. This test helps identify whether rosuvastatin may be the cause.
Should I stop taking rosuvastatin while awaiting results?
Do not change your medication without speaking with your clinician. If you have significant bleeding, unusual bruising, or symptoms of a low platelet count, seek prompt medical advice.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy