Rosuvastatin-Induced Platelet IgM Antibody, Serum/Plasma — Qualitative, Flow Cytometry
A specialized test that looks for IgM antibodies that bind to platelets in the presence of rosuvastatin, which may support a drug-induced immune platelet reaction.
["A positive result can support rosuvastatin-related immune thrombocytopenia when combined with your platelet count, symptoms, and medication history."]
Key facts at a glance
- LOINC
- 73156-2
- Short code
- Rosuvastatin ind plt IgM SerPl Ql FC
- Synonyms
- Rosuvastatin ind plt IgM SerPl Ql FC
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test looks for IgM antibodies that attach to platelets when rosuvastatin is present. These antibodies may be associated with an immune reaction that causes platelet destruction and lowers the platelet count.
Why might I need this test?
Your clinician may order it if you take or recently took rosuvastatin and developed a low platelet count, bruising, nosebleeds, petechiae, or bleeding that is harder than usual. It is generally a specialized test used when a drug-related immune platelet reaction is suspected.
How is the test performed?
A blood sample is collected, and the serum or plasma is tested using flow cytometry. The laboratory compares platelet antibody binding with and without rosuvastatin to determine whether a drug-dependent reaction is present.
How do I prepare for the test?
Fasting is usually not required. Tell the laboratory and your clinician about rosuvastatin use, when it was started or stopped, other medicines and supplements you take, and any bleeding symptoms. Do not stop a prescribed medicine without medical advice.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive result indicates that rosuvastatin-dependent IgM binding to platelets was detected, which can support a drug-induced immune platelet reaction. A negative result does not completely exclude the reaction. Results should be interpreted with your platelet count, bleeding symptoms, medication history, and other laboratory findings by your clinician.
Short name
Rosuvastatin-induced platelet IgM
Frequently asked questions
Does a positive result mean rosuvastatin is unsafe for me?
Can this test explain bruising or bleeding?
What if the result is negative but my platelet count is low?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy