Serum or plasma concentration of a substance related to donor red blood cell compatibility screening (e.g., antibody detection for transfusion safety)
This test checks for antibodies in your blood that may react with donor red blood cells, helping ensure safe blood transfusions.
["It helps prevent transfusion reactions by identifying potential red blood cell incompatibilities."]
Key facts at a glance
- LOINC
- 47360-3
- Short code
- RPR Ser Donr Ql
- Synonyms
- RPR Ser Donr Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- rpr
- CPT
- 86592
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you’re a blood donor or if you’re scheduled for a blood transfusion. It’s also used in certain medical evaluations to assess immune responses related to red blood cell compatibility.
What to Expect Before the Test
You’ll typically provide a blood sample by venipuncture. The test involves collecting serum or plasma, which is then analyzed for specific antibodies that could affect blood compatibility.
What the Test Measures
The test detects the presence and concentration of antibodies (like anti-D or other red blood cell antibodies) that could cause adverse reactions if they react with donor red blood cells during a transfusion.
How the Results Are Used
Results help determine if you’re a suitable donor or if additional testing is needed before a blood transfusion. Positive results may require further evaluation to rule out specific antibody profiles.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
RPR Serology (Donor Screening)
Frequently asked questions
What does a positive result mean?
How often should I get this test?
Can I donate blood if I have a positive result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy