Serum or Plasma Creatinine Concentration (Mass Concentration)
This test measures the amount of creatinine, a waste product from muscle breakdown, in your blood or plasma. It helps assess how well your kidneys are filtering blood.
["A key test for kidney function and overall health."]
Key facts at a glance
- LOINC
- 76643-6
- Short code
- RR.sd (HR var)
- Synonyms
- RR.sd (HR var)
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ekg
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Your Kidneys Matter
Your kidneys are vital organs that filter waste and excess substances from your blood, helping to maintain your body’s chemical balance. Creatinine is a byproduct of muscle metabolism that your kidneys remove from your blood. If your kidneys aren’t working well, creatinine levels can build up, which may indicate kidney problems.
What This Test Detects
Creatinine levels in your blood or plasma are measured to determine how efficiently your kidneys are filtering waste. Higher levels may suggest reduced kidney function, while lower levels might indicate overhydration or other conditions.
How the Test Works
A small blood sample is taken from your arm and sent to a lab. The lab uses a specialized method (often automated) to measure creatinine concentration. Results are typically reported in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L).
What Your Results Mean
Kidney function is often assessed alongside other tests, such as blood urea nitrogen (BUN). While creatinine alone doesn’t diagnose kidney disease, it’s a useful marker when combined with clinical symptoms and other tests. Your doctor will interpret results in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated creatinine levels can signal kidney damage or disease, especially if accompanied by symptoms like fatigue, swelling, or changes in urine output. Low levels may reflect dehydration or other conditions but are less commonly concerning unless part of a broader evaluation. Regular monitoring is important for people with chronic conditions like diabetes or hypertension.
Short name
Creatinine Level (Serum/Plasma)
Frequently asked questions
What causes creatinine levels to change?
Can diet affect creatinine levels?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy