Skip to content

Vitamin D Binding Protein (DBP) or Serum Protein Related to Vitamin D Metabolism (immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of a protein in your blood that helps transport vitamin D. It may be used alongside vitamin D levels to assess vitamin D status or related metabolic processes.

Quick summary

["This test helps evaluate how vitamin D is processed in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9574-5
Short code
RSV IgM Titr Ser IF
Synonyms
RSV IgM Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Your healthcare provider may order this test to check the levels of vitamin D-binding protein (DBP), a protein in your blood that binds to vitamin D and other fat-soluble vitamins. This protein plays a role in transporting these vitamins throughout your body. The test helps assess how well your body is utilizing vitamin D and other fat-soluble vitamins.

Why It Might Be Ordered

Doctors may order this test if you have symptoms of vitamin D deficiency, kidney disease, or liver conditions. It can also be part of a broader evaluation for metabolic disorders or when monitoring certain medications that affect vitamin metabolism.

Common Reasons for Testing

Tests like this are sometimes performed when there are concerns about how well your body is managing fat-soluble vitamins. It may be used in conjunction with vitamin D levels to provide a more complete picture of your metabolic health.

Sample Collection and Preparation

A blood sample is typically drawn from a vein in your arm. You may be asked to fast for a few hours before the test, depending on your healthcare provider’s instructions. The blood is then sent to a lab for analysis using an immunoassay method to measure the protein concentration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vitamin D Binding Protein Level

Frequently asked questions

How does this test relate to my overall health?
This test helps evaluate the function of proteins involved in transporting fat-soluble vitamins, including vitamin D. Abnormal levels may indicate issues with vitamin metabolism, kidney function, or liver health. It can also be part of diagnosing or monitoring conditions like hypovitaminosis D or certain genetic disorders affecting protein synthesis.
What does a high or low result mean?
While specific interpretations depend on clinical context, elevated levels of vitamin D-binding protein might suggest conditions like nephrotic syndrome or certain liver diseases. Lower-than-expected levels could be associated with kidney dysfunction or other metabolic issues. Your results should be discussed with your healthcare provider.
Can this test be done at home?
No, this test requires a blood sample collected by a healthcare professional. Results are typically reviewed by a medical provider to assess your health and guide treatment decisions.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy