Protein Electrophoresis (Serum/Plasma) with Bromocresol Green (BCG) Dye Binding

What This Test Measures

The bromocresol green dye binds to specific protein groups in your blood sample. As the dye binds, it shifts color, allowing lab technicians to separate and quantify different protein components. This includes albumin, globulins, and other protein fractions that may indicate underlying health issues.

Why It’s Done

Your healthcare provider may order this test to evaluate conditions like chronic kidney disease, liver dysfunction, or certain types of anemia. It can also help monitor protein loss or abnormalities in conditions such as multiple myeloma or nephrotic syndrome.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The sample is then processed to separate serum or plasma, where the bromocresol green dye is added to perform the electrophoresis. This process separates proteins based on size and charge.

Common Conditions Monitored

This test is particularly useful for identifying imbalances in protein levels that may signal kidney problems (e.g., albuminuria), liver disease (e.g., reduced albumin), or immune system disorders (e.g., elevated globulins).