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Vitamin D Binding Protein (DBP) – Serum or Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a protein in your blood that helps transport vitamin D. It can be important for certain health assessments.

Quick summary

["This test helps evaluate how your body may handle vitamin D and related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31956-6
Short code
RUBV Ag Cvx Ql
Synonyms
RUBV Ag Cvx Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Vitamin D Binding Protein (DBP) is a protein in your blood that binds to vitamin D and other fat-soluble vitamins. It helps transport these vitamins throughout your body. Your body produces this protein naturally, and its levels can be influenced by various health factors, including kidney function and genetic predispositions.

Why Might You Need This Test?

Doctors may order this test if you have symptoms or conditions linked to vitamin D metabolism, such as kidney disease, certain genetic disorders, or if you’re being monitored for vitamin D-related issues. It can also be part of broader evaluations for conditions affecting vitamin metabolism.

How Is This Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab where it is analyzed using an immunoassay or similar method to measure the concentration of Vitamin D Binding Protein.

What Are Possible Results?

Results are typically reported as a concentration value (e.g., in grams per liter). While reference ranges can vary by lab, abnormal levels may suggest underlying health concerns that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D Binding Protein levels can be relevant in diagnosing or monitoring conditions like nephrotic syndrome, certain genetic disorders (e.g., vitamin D-dependent rickets), or kidney dysfunction. It may also be used in research or specialized clinical scenarios where vitamin D metabolism is a focus.

Short name

Vitamin D Binding Protein

Frequently asked questions

What does a low or high Vitamin D Binding Protein level mean?
Low levels may indicate conditions affecting protein synthesis or kidney function, while high levels could be associated with certain genetic or metabolic disorders. Your doctor will interpret results in the context of your overall health and symptoms.
The frequency depends on your medical condition and why the test was ordered. Your healthcare provider will determine the best timing based on your individual needs.
While lifestyle factors like diet and exercise can influence overall health, they may not directly impact Vitamin D Binding Protein levels. However, conditions like kidney disease or genetic factors are primary drivers of these levels.
The blood draw itself may cause a slight pinch or discomfort, but it is generally brief and well-tolerated. Most people experience minimal discomfort afterward.
Always discuss your test results and any concerns with your healthcare provider. They can explain what your results mean in relation to your health and recommend next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy