Vitamin B12 (Serum) with Quantitative Measurement
This test measures the level of vitamin B12, a crucial nutrient that helps your body make healthy red blood cells and nerve tissue. Low levels may indicate deficiencies or underlying health conditions.
["Vitamin B12 levels help check for deficiencies that could affect your energy, nerve function, or blood health."]
Key facts at a glance
- LOINC
- 14527-6
- Short code
- RUBV Ag Nose Ql IF
- Synonyms
- RUBV Ag Nose Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Vitamin B12 is essential for red blood cell production, nerve function, and DNA synthesis. Your body absorbs it primarily from food, and deficiencies can develop over time if intake is insufficient or absorption is impaired. This test helps identify whether your levels are within a healthy range or if further investigation is needed.
What to Expect Before the Test
No special preparation is needed for this test. You may have a blood sample drawn from a vein in your arm by a healthcare professional. If you’re on a vitamin B12 supplement or have recent vitamin B12-rich foods, your provider may advise timing your intake around the test to avoid interference.
Common Causes of Low or High Levels
Low vitamin B12 levels can result from dietary deficiencies, conditions affecting absorption (like pernicious anemia or celiac disease), chronic illnesses, or certain medications. High levels are less common but may occur with long-term vitamin B12 supplements or rare genetic disorders.
Symptoms to Watch For
Symptoms of vitamin B12 deficiency may include fatigue, weakness, numbness or tingling in hands/feet, balance issues, memory problems, or unusual mood changes. If you experience these symptoms, discuss them with your doctor, as early diagnosis and treatment can prevent complications.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Vitamin B12 (Serum)
Frequently asked questions
What does a low vitamin B12 level mean?
Does diet affect vitamin B12 test results?
Can vitamin B12 levels be high?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy