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Vitamin E (alpha-tocopherol) quantitative measurement in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant, in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports immune function and may lower heart disease risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85796-1
Short code
RUBV E1 Ct Spec Qn NAA+probe
Synonyms
RUBV E1 Ct Spec Qn NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for vitamin E deficiency, which can occur due to certain medical conditions, malabsorption issues, or long-term use of certain medications. It may also be used to monitor vitamin E levels in people taking supplements or those with genetic disorders affecting fat metabolism.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for 8–12 hours before the test if your provider specifies it, but this is not always required. Bring any medications or supplements you’re taking to your appointment.

How the Test Is Performed

A blood sample is drawn from a vein in your arm by a healthcare professional. The blood is sent to a lab for analysis using an immunoassay method to measure vitamin E levels.

What the Results Mean

Results are compared to reference ranges, but exact values can vary by lab. Low levels may indicate deficiency, while high levels could suggest over-supplementation or certain conditions. Your provider will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Vitamin E Deficiency Can Affect Multiple Systems

Short name

Vitamin E Level

Frequently asked questions

What Are Common Causes of Low Vitamin E Levels?
Low vitamin E levels can result from conditions like celiac disease, cystic fibrosis, or liver disease, which impair fat absorption. Rare genetic disorders, long-term use of certain medications (e.g., anticonvulsants), or malabsorption syndromes (e.g., Crohn’s disease) may also lead to deficiency.
How Might High Vitamin E Levels Be Treated?
High vitamin E levels are less common but may require medical evaluation to identify underlying causes, such as liver disease or certain medications. Your provider may adjust supplements or monitor your condition closely.
Can Vitamin E Supplements Affect This Test?
Yes, taking high-dose vitamin E supplements may temporarily alter test results. If you’re on supplements, discuss timing with your provider to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy