Cerebrospinal Fluid (CSF) Protein by Fluorescence Immunoassay (Qualitative)
This test measures the protein content in your cerebrospinal fluid (the fluid surrounding your brain and spinal cord) using a fluorescence-based method. It helps assess conditions affecting the blood-brain barrier or the brain itself.
["This test helps diagnose or monitor conditions like meningitis, brain tumors, or other neurological issues by checking for abnormal protein levels in CSF."]
Key facts at a glance
- LOINC
- 17551-3
- Short code
- RUBV IgG CSF IA-aCnc
- Synonyms
- RUBV IgG CSF IA-aCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, confusion, or neurological problems. It’s often used alongside other tests, such as a lumbar puncture, to investigate conditions like infections, inflammation, or tumors in the central nervous system.
What to Expect Before the Test
You’ll typically undergo a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect CSF. The procedure is usually quick and done in a hospital setting. No special preparation is needed, but inform your doctor about any medications you’re taking.
What the Results Mean
Protein levels in CSF can vary widely depending on the underlying condition. Elevated protein levels may suggest conditions like meningitis, multiple sclerosis, or brain tumors. Lower-than-expected levels might indicate issues with CSF production or circulation. Your doctor will interpret the results in the context of your symptoms and other tests.
Common Conditions This Test Helps Diagnose
This test is particularly useful for diagnosing or monitoring conditions such as viral or bacterial meningitis, encephalitis, subarachnoid hemorrhage, brain tumors (like gliomas), and inflammatory diseases like multiple sclerosis.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Protein (Qualitative)
Frequently asked questions
How is this test different from a general protein test in blood?
Will I need to fast before this test?
What are the typical reference ranges for CSF protein?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy