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Vitamin D Binding Protein (DBP) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of vitamin D binding protein, a protein in your blood that helps transport vitamin D and other fat-soluble vitamins.

Quick summary

["Understanding your vitamin D binding protein levels can help assess vitamin D metabolism and related health risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74415-1
Short code
RUBV IgG Fld Ql IA
Synonyms
RUBV IgG Fld Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Vitamin D Binding Protein?

Vitamin D binding protein (DBP) is a carrier protein in your blood that binds to vitamin D and other fat-soluble vitamins, helping them stay in circulation. It also plays a role in transporting hormones and other molecules. This test helps evaluate how well your body is processing these substances.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms related to vitamin D deficiency, kidney or liver conditions, or if you’re being monitored for conditions like hypercalcemia or certain metabolic disorders. It can also be part of broader evaluations for genetic disorders affecting protein function.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is then processed to separate serum (the liquid part after clotting) for analysis. The test measures the concentration of DBP in your blood using an immunoassay method, which detects the protein’s presence and quantity.

What Do the Results Mean?

Results are typically reported as a concentration value (e.g., grams per liter). While reference ranges can vary by lab, abnormal levels may suggest conditions like hypophosphatemia, kidney disease, or certain genetic disorders affecting protein metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D binding protein levels can be important in diagnosing or monitoring conditions related to vitamin D metabolism, kidney function, or genetic disorders. For example, low levels may indicate kidney issues, while high levels could be associated with certain metabolic or hormonal imbalances. It’s often used alongside other tests to provide a clearer picture of your health.

Short name

DBP

Frequently asked questions

What causes abnormal vitamin D binding protein levels?
Abnormal levels of vitamin D binding protein can result from kidney disease, liver disease, certain genetic conditions (like hereditary angioedema), or hormonal imbalances. Lifestyle factors, such as malnutrition or chronic illness, may also play a role.
How long does it take to get results?
Test results are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Your doctor will contact you once the results are ready.
Can I eat or drink before this test?
You can typically eat and drink normally before this test unless your doctor specifies otherwise. Avoid alcohol or certain medications that may affect blood composition for 24 hours before your appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy