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C-reactive protein (CRP) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein made by your liver in response to inflammation in your body.

Quick summary

["CRP helps identify and monitor inflammation, often used to check for infections, autoimmune conditions, or other health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86688-9
Short code
RVC Spec Ql Cult
Synonyms
RVC Spec Ql Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order CRP testing to evaluate signs of inflammation, assess risk for heart disease, or monitor conditions like arthritis, infections, or other inflammatory diseases. It can also help guide treatment decisions.

What to Expect Before the Test

No special preparation is needed for this blood test. You may be asked to fast for 8–12 hours before the draw if your lab requires it, but this is not always the case for CRP. Bring any medications or questions to your appointment.

What Happens During the Test?

A healthcare provider will draw blood from a vein, usually in your arm. You may feel a small pinch, but it usually doesn’t cause significant discomfort. The test takes a few minutes, and you can resume normal activities afterward.

What Does the Test Result Mean?

Results are interpreted based on your overall health and symptoms. Higher-than-normal levels may suggest inflammation, infections, or certain diseases, while lower levels may indicate reduced inflammation. Your doctor will discuss the meaning of your specific result with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP

Frequently asked questions

CRP is a marker for inflammation and is often used alongside other tests to diagnose conditions like infections, autoimmune diseases (e.g., rheumatoid arthritis), or cardiovascular risks. It can also help track how well treatments are working.
CRP levels can vary based on factors like age, sex, and overall health. If you have a chronic condition, your doctor may monitor CRP regularly to check for changes in inflammation over time.
CRP is not a definitive test for a single disease but is often used as part of a broader evaluation. It’s important to discuss your results with your healthcare provider.
CRP testing is generally safe and has few risks. Rarely, you may experience bruising, mild pain, or swelling at the injection site. If you have a bleeding disorder or take blood thinners, let your doctor know before the test.
If you have a history of high CRP levels, your doctor may recommend lifestyle changes (like diet or exercise) or medications to help manage inflammation.
CRP results may be affected by recent illness, stress, or certain medications. If you’re unsure about your test results, ask your doctor to clarify what they mean for your health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy