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C-reactive protein (CRP) by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by the liver in response to inflammation, helping assess low-level inflammation or infection in your body.

Quick summary

["Helps track subtle signs of inflammation that may not show up in other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8813-8
Short code
RV EF 2D Echo
Synonyms
RV EF 2D Echo
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
d-echo
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Your doctor may order a CRP (C-reactive protein) blood test when they suspect inflammation somewhere in your body. It is often used to look into symptoms such as fever, fatigue, or unexplained pain, to monitor a long-term condition, or to see whether a treatment is working as expected.

Your healthcare provider may order this test to check for early signs of inflammation, monitor conditions like autoimmune diseases, or evaluate risk factors for heart disease or other health issues. High-sensitivity CRP is particularly useful for detecting mild inflammation that might not be detected by standard CRP tests.

Very little preparation is needed for a CRP blood test. You can usually eat and drink normally beforehand, and you can generally keep taking your regular medications unless your doctor tells you otherwise. Let the person drawing your blood know if you have ever felt faint during a blood draw.

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your provider know before the test.

CRP results are reported in milligrams per liter (mg/L). Higher-than-normal levels usually point to inflammation somewhere in the body, which may come from an infection, an injury, or a chronic illness. A single high result does not reveal the exact cause, so your doctor will review it alongside your symptoms and other test results.

Results are not provided as a single numeric range since reference values vary by lab and condition. Your provider will interpret the result in relation to your overall health and symptoms. Elevated levels may suggest inflammation, infection, or other underlying health concerns.

CRP testing is commonly used to follow conditions that involve ongoing inflammation, such as rheumatoid arthritis, lupus, inflammatory bowel disease, infections, and recovery after surgery or injury. Repeat tests over time can show whether treatment is bringing inflammation under control.

This test is often used to monitor conditions such as cardiovascular risk, rheumatoid arthritis, lupus, or other inflammatory diseases. It can also help guide treatment decisions for chronic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP (High-Sensitivity)

Frequently asked questions

What does a high CRP level mean?
What does it mean if my CRP test result is lower than the normal reference range?
A low CRP level usually suggests minimal inflammation. However, it doesn’t rule out all possible causes of symptoms, so your provider may recommend additional tests if needed.
Can healthy lifestyle changes such as regular exercise, weight loss, and quitting smoking help lower my CRP levels?
Yes, lifestyle factors like diet, exercise, and stress management can influence inflammation levels. Making positive lifestyle changes may help lower CRP and improve overall health.
Your provider will determine how often to check your CRP levels based on your health needs. Some people may need it yearly, while others may need it more frequently depending on their condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy