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Vitamin D Binding Protein (DBP) or Serum Vitamin D Binding Protein

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of Vitamin D Binding Protein (DBP) in your blood. DBP helps transport vitamin D and other hormones in the bloodstream.

Quick summary

["DBP levels may be checked if you have vitamin D deficiency or related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81388-1
Short code
RV EF 3D US
Synonyms
RV EF 3D US
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-d
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms of vitamin D deficiency, such as muscle weakness, bone pain, or fatigue. It may also be used to monitor conditions like hypophosphatasia or certain genetic disorders affecting vitamin D metabolism.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein.

How the Test Is Performed

A healthcare professional will insert a needle into a vein in your arm to draw blood. You may feel a small pinch, but the procedure is quick and typically painless.

What the Results Mean

High or low levels of DBP alone may not directly indicate vitamin D status, but they can be part of a broader evaluation. Your provider will interpret results in relation to your clinical picture and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

DBP

Frequently asked questions

What questions might you have about this test?
This test measures DBP levels but does not directly assess vitamin D levels. If you’re concerned about vitamin D deficiency, ask your provider about related tests like serum 25-hydroxy vitamin D.
Will I need to fast for this test?
Sometimes fasting is recommended for blood tests, but for DBP specifically, fasting may not be required unless your provider specifies otherwise.
Can I take my usual medications before the blood draw?
Yes, you can typically take your medications as usual unless your provider advises otherwise. Some medications may affect blood test results, so always check with them beforehand.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy