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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle breakdown, in your serum. It helps assess kidney function by checking how well your kidneys filter blood.

Quick summary

["A creatinine test helps doctors evaluate kidney health and diagnose kidney disease early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8817-9
Short code
RV EF Spiral CT
Synonyms
RV EF Spiral CT
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct-spiral
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle metabolism that your kidneys filter out of your blood. High levels can indicate poor kidney function, while low levels might suggest dehydration or muscle loss. This test is often used alongside other kidney function tests, like blood urea nitrogen (BUN), to get a full picture of kidney health.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. If you’re on a low-protein diet or have had recent muscle activity, your doctor may advise adjustments to avoid misleading results.

Common Reasons for Testing

Doctors order creatinine tests to monitor kidney function, especially if you have symptoms like swelling, fatigue, or changes in urine output. It’s also used during pregnancy, before surgeries, or when managing conditions like diabetes or heart disease.

What the Results Mean

Results are compared to your body’s size (height/weight) and overall health. High levels may signal kidney problems, while very low levels could indicate dehydration or muscle wasting. Your doctor will interpret results in the context of your medical history and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status. For example, people with kidney disease may need tests every few months, while healthy individuals might only need it if they have risk factors like high blood pressure or diabetes.
What can affect my creatinine levels?
Several factors can influence creatinine levels, including muscle mass (more muscle = higher levels), dehydration, recent exercise, or certain medications. If you’ve had recent changes in activity or diet, let your doctor know to avoid misleading results.
What if my results are out of the normal range?
If your results are high, your doctor may recommend further tests or adjustments to your treatment plan. If they’re low, they might check for dehydration or other conditions affecting muscle metabolism. Always discuss your results with your healthcare provider for personalized guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy