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Vitamin E (alpha-tocopherol) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant found in your blood. Low levels may indicate poor absorption or nutritional deficiencies.

Quick summary

["Vitamin E helps protect cells from damage and supports immune function; check if you have symptoms of deficiency or need monitoring for dietary intake."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106750-3
Short code
RV ES vol MR
Synonyms
RV ES vol MR
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like muscle weakness, nerve problems, or frequent infections. It’s also used to monitor vitamin E levels in people with certain digestive disorders (e.g., celiac disease) or malabsorption syndromes.

What to Expect Before the Test

No special preparation is needed. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s instructions. Bring any medications you’re taking.

How the Test Works

A blood sample is drawn from a vein in your arm. The sample is sent to a lab where it’s analyzed to measure vitamin E levels using a specialized method (likely immunoassay or chromatography).

What the Results Mean

Results are compared to a reference range for your age and health status. Low levels may suggest dietary deficiencies, malabsorption, or certain genetic conditions. High levels could indicate over-supplementation or liver disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin E deficiency is rare but can cause neurological issues, muscle weakness, or immune dysfunction. Regular monitoring is important for people with conditions like cystic fibrosis, Crohn’s disease, or long-term fat malabsorption. High levels may raise concerns about liver function or excessive vitamin E intake.

Short name

Vitamin E Level

Frequently asked questions

What causes low vitamin E levels?
Low vitamin E levels can result from poor dietary intake, digestive disorders (e.g., celiac disease, pancreatitis), bile duct blockages, or certain medications that interfere with absorption.
What symptoms might low vitamin E cause?
Symptoms of deficiency may include muscle weakness, balance problems, nerve damage, or frequent infections. Some people may not notice symptoms until they’re severe.
How is vitamin E deficiency treated?
Treatment often involves dietary changes (e.g., more nuts, seeds, or fortified foods) or vitamin E supplements if absorption is impaired. Your provider may adjust your supplement dose based on test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy