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Routine Serum Autoantibody Profile (Screening)

Published: August 9, 2026Updated: August 16, 2026

This test checks for certain proteins in your blood that your immune system mistakenly identifies as foreign, which may indicate conditions like autoimmune diseases.

Quick summary

["Helps identify potential autoimmune disorders by detecting abnormal proteins in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71763-7
Short code
RV IgA Titr Ser IA
Synonyms
RV IgA Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for a range of autoantibodies, including those that may target proteins in your joints, skin, blood vessels, or other tissues. These antibodies can signal inflammation or damage in the body, often linked to autoimmune conditions like lupus, rheumatoid arthritis, or others.

Common Conditions Linked to Positive Results

Positive results may suggest conditions such as systemic lupus erythematosus (SLE), rheumatoid arthritis, scleroderma, or other autoimmune diseases. However, a single positive test does not confirm a diagnosis—further evaluation is needed.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like joint pain, fatigue, rash, or unexplained fever, or if you have a family history of autoimmune diseases.

What to Expect Before the Test

No special preparation is needed. You may fast before the test, but your provider will confirm if fasting is required for accuracy. Bring any medications you’re taking, as some may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Autoantibody Screen (Serum)

Frequently asked questions

Autoantibodies can be present in many people without disease, so results should be interpreted by a healthcare professional alongside symptoms and other tests. False positives or negatives can occur, so follow-up testing may be recommended.
This test is primarily a screening tool and does not diagnose autoimmune diseases. If results are abnormal, your doctor may order additional tests to confirm or rule out specific conditions.
How long will I need to wait for results?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will discuss them with you during your follow-up visit.
Can I take my medications before this test?
Yes, you can take your usual medications as scheduled unless instructed otherwise by your provider. Some medications may affect antibody levels, so always confirm with your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy