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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A key measure of kidney function and filtering efficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10002-4
Short code
R wave dur L-II
Synonyms
R wave dur L-II
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters in Kidney Health

Creatinine levels help doctors determine if your kidneys are working properly. High levels may indicate reduced kidney function or kidney disease, while low levels could suggest overhydration or muscle disorders.

How the Test Works

Your blood or plasma is collected and analyzed using a method that detects creatinine’s concentration. The test does not require fasting and is typically done as part of a routine kidney function panel.

When You Might Need This Test

Your doctor may order this test if you have symptoms like swelling, fatigue, frequent urination, or if you have a history of kidney problems, diabetes, or high blood pressure.

What to Expect Before the Test

No special preparation is needed. You may drink water beforehand, but avoid alcohol or excessive fluids 24 hours before testing to get an accurate result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine

Frequently asked questions

How does creatinine relate to kidney function?
How often should I get this test?
Your doctor will determine the frequency based on your health status. Regular monitoring may be recommended if you have chronic kidney disease, diabetes, or other conditions affecting kidney function.
Can diet affect creatinine levels?
What if my results are abnormal?
Abnormal results may prompt further testing or evaluation of your kidney health. Your doctor will discuss the findings with you and may recommend lifestyle changes, medications, or additional tests to address any concerns.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy