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Total IgE (Immunoglobulin E) Antibody Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) antibodies in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to parasites.

Quick summary

["IgE levels help identify allergies or immune responses to certain triggers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61312-5
Short code
Rye IgE/IgE total %
Synonyms
Rye IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE (Immunoglobulin E) is a type of antibody produced by your immune system. It’s primarily involved in allergic reactions and responses to allergens like pollen, dust mites, or certain foods. When your body detects these substances, IgE helps trigger the release of chemicals that cause symptoms such as sneezing, itching, or swelling.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms of allergies, such as asthma, hay fever, eczema, or unexplained skin rashes. It can also help diagnose conditions like allergic rhinitis, food allergies, or certain parasitic infections. Sometimes, it’s used to monitor immune responses in people with chronic conditions.

How Is the Test Performed?

A small blood sample is taken from a vein in your arm. The sample is then sent to a lab, where it’s analyzed to measure the total IgE antibody level. The test typically takes a few days to return results.

What Do Your Results Mean?

Results can vary widely depending on your health, age, and other factors. Elevated IgE levels may suggest allergies or immune-related conditions, while normal or low levels might indicate fewer allergic responses. Your doctor will interpret the results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

How often do I need to retest if my IgE levels change?
If your IgE levels are elevated and linked to allergies or other conditions, your doctor may recommend retesting after treatment or if symptoms persist. Follow their guidance for follow-up testing, as timing depends on your specific situation.
Can IgE levels be affected by other medications or conditions?
Yes, certain medications (like antihistamines or steroids) or underlying health conditions (such as asthma or autoimmune diseases) can influence IgE levels. Always inform your doctor about all medications or conditions you have before the test.
Is there anything I should avoid before the blood draw?
No specific preparations are needed for this test, but avoid taking antihistamines or other allergy medications for a few days before the test if your doctor advises it. Otherwise, rest assured that fasting or other restrictions may not apply.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy