S100 Calcium Binding Protein B Serum
This test measures the concentration of S100 calcium-binding protein B in your blood serum. It may be used to assess certain conditions affecting brain or nerve cells.
["This test helps evaluate potential nerve or brain-related health concerns."]
Key facts at a glance
- LOINC
- 83114-9
- Short code
- S100 Ca binding protein B Ser IA-mCnc
- Synonyms
- S100 Ca binding protein B Ser IA-mCnc
- Category
- electrolyte
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
S100CB is a protein found in small amounts in the brain and nervous system. When certain conditions affect these tissues, levels of S100CB can rise in the blood. This test detects the presence of this protein in your serum.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like headaches, confusion, seizures, or neurological issues. It may also be used in research or specialized diagnostic contexts for conditions such as brain tumors, multiple sclerosis, or nerve damage.
How Is the Sample Collected?
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum, which is sent for testing.
What Are Common Uses?
While S100CB is not commonly used in routine clinical practice, it can be part of specialized diagnostic workups for neurological or brain-related disorders. It may also be studied in research settings for conditions affecting the central nervous system.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated levels of S100CB in the blood can sometimes indicate damage or disease affecting the brain or nervous system. However, its clinical utility is limited and typically reserved for research or highly specialized diagnostic scenarios. False elevations may occur with certain medications or conditions, so results should be interpreted by a healthcare provider in the context of your overall health and symptoms.
Short name
S100CB Protein (Serum)
Frequently asked questions
Why might my doctor order this test?
What are the typical reference ranges for this test?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy