Skip to content

S100 Calcium-Binding Protein (S100C) Serum Binding Protein Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of S100 calcium-binding protein in your blood, which may help assess certain inflammatory or tissue damage conditions.

Quick summary

["This test helps doctors evaluate conditions affecting soft tissues or inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47275-3
Short code
S100 Ca binding protein B Ser-mCnc
Synonyms
S100 Ca binding protein B Ser-mCnc
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

S100C is a group of proteins that bind calcium and are involved in regulating cell processes. In blood, its binding protein form is analyzed here. Elevated levels may indicate conditions like soft tissue injuries, certain cancers, or inflammatory diseases.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like unexplained pain, swelling, or signs of tissue damage. It can also be part of monitoring for conditions like certain cancers or chronic inflammatory disorders.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then sent to a lab for analysis using a specialized immunoassay method to detect the binding protein levels.

What Are Possible Results?

Results are not provided with specific numeric ranges. Interpretation depends on clinical context, symptoms, and other test results. Your doctor will discuss findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

S100C Binding Protein Test

Frequently asked questions

How often will I need this test?
This test is typically ordered as needed based on your symptoms or medical condition. Your doctor will determine how often it should be repeated.
What do abnormal results mean?
Abnormal results may suggest underlying conditions such as soft tissue injuries, certain cancers, or inflammatory processes. However, results must be evaluated in combination with your medical history, symptoms, and other tests.
Can I prepare for this test?
No special preparation is needed for this blood test. You may continue with your usual activities, but avoid heavy exercise before the test if advised by your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy