Hepatitis B surface antigen (HBsAg) antibody detection (qualitative, serum/plasma)
This test checks for the presence of antibodies against the hepatitis B surface antigen, which your immune system produces in response to infection with the hepatitis B virus.
["Helps determine if your body has fought off hepatitis B or if you’re immune to the virus."]
Key facts at a glance
- LOINC
- 88273-8
- Short code
- S agalactiae hsp60 Bld Pos Ql Probe
- Synonyms
- S agalactiae hsp60 Bld Pos Ql Probe
- Category
- coagulation
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects specific antibodies (immunoglobulins) that your immune system makes after exposure to the hepatitis B virus. These antibodies are a sign that your body has either recovered from hepatitis B or has built immunity through vaccination. The test is qualitative, meaning it only tells you whether antibodies are present or not, not their exact amount.
Why It’s Ordered
Doctors may order this test to evaluate your immunity to hepatitis B, screen for past infection, or confirm vaccination success. It’s also used in high-risk groups (e.g., healthcare workers, travelers) to monitor protection status.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The blood is processed into either serum or plasma for testing. This test does not require fasting and is typically done in a lab setting.
What to Expect Before the Test
You may feel slight discomfort from the needle, but most people tolerate blood draws well. Avoid heavy exercise or alcohol 24 hours before the test to ensure accurate results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
HBsAg Antibody (Qualitative)
Frequently asked questions
Positive result: Indicates your body has produced antibodies against hepatitis B, meaning you’ve either recovered from infection or are immune due to vaccination. Negative result: Suggests no current immunity, so you may need vaccination or further testing if at risk of exposure.
What does a positive result mean for my health?
Can I get hepatitis B if I have a positive antibody test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy