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Serum or plasma substance concentration for serum/plasma creatinine

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys are filtering waste products from your blood, specifically creatinine.

Quick summary

["Kidney function depends on this test to detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
80175-3
Short code
SAH SerPl-sCnc
Synonyms
SAH SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Creatinine is a waste product from muscle metabolism that kidneys filter out of your blood. Elevated levels may indicate reduced kidney function, while lower levels could suggest overhydration or muscle breakdown. This test helps assess kidney health and diagnose conditions like chronic kidney disease.

Why Might You Need This Test?

Your doctor may order this test to monitor kidney function, especially if you have risk factors like diabetes, high blood pressure, or a family history of kidney disease. It’s also used before certain procedures, to check for kidney issues before they become serious.

What to Expect Before the Test

No special preparation is needed unless instructed. You may be asked to fast for 8–12 hours before the test if it’s part of a metabolic panel. Bring any medications you’re taking, as some may affect results.

What to Expect During the Test

A small needle will draw blood from a vein in your arm. It usually takes a few minutes, and you may feel a brief pinch. The blood is then sent to a lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and risk factors. For example, people with diabetes or kidney disease may need it more frequently than others.
Can diet or exercise affect my creatinine levels?
Dietary changes like eating more protein can temporarily raise creatinine levels, but your doctor will consider this when interpreting results. Exercise generally doesn’t affect creatinine levels unless it causes muscle damage.
What if my results are outside the normal range?
If your results are abnormal, your doctor will discuss them with you and may recommend additional tests or treatments. They’ll also check for other factors that could influence your results, such as hydration status or medications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy