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Serum or Plasma Substance Concentration of Arginine (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of arginine, an essential amino acid, in your blood. Arginine plays a key role in protein synthesis, hormone regulation, and detoxification processes.

Quick summary

["Understanding your arginine levels can help assess metabolic health and certain genetic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75147-9
Short code
SAICAR CSF-sCnc
Synonyms
SAICAR CSF-sCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to amino acid imbalances, such as metabolic disorders, liver disease, or kidney problems. It could also be part of a broader evaluation for genetic testing or monitoring of certain inherited metabolic diseases.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw. Avoid consuming foods or supplements rich in arginine (e.g., certain protein supplements) for 24 hours prior to testing if instructed.

What the Test Results Mean

Results are compared to a reference range specific to your age, sex, and overall health. Abnormal levels may indicate metabolic issues, genetic disorders, or conditions affecting protein metabolism.

Common Conditions Monitored

Elevated arginine levels might be seen in conditions like urea cycle disorders or certain liver diseases, while low levels could suggest kidney dysfunction or other metabolic abnormalities.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Arginine Levels and Health

Short name

Arginine Level

Frequently asked questions

What does my arginine level tell me about my health?
Your arginine level can help identify whether you have a metabolic disorder, such as an inherited condition affecting amino acid metabolism. It may also provide clues about how well your kidneys or liver are functioning. Always discuss your results with your healthcare provider for personalized interpretation.
How often will I need this test?
The frequency depends on your medical condition and treatment plan. Some patients may need this test periodically to monitor changes in their arginine levels or overall health. Your provider will determine the best schedule for you.
Can arginine levels change with diet?
Yes, arginine levels can be influenced by diet. Consuming foods high in protein or supplements containing arginine may temporarily alter your results. If your test is part of a routine check, avoid dietary changes unless instructed by your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy