Salicylate concentration (serum/plasma)
This test measures the amount of salicylate, a compound found in aspirin, in your blood. It helps assess whether you’ve ingested too much aspirin or are experiencing toxicity.
["Salicylate levels help monitor aspirin exposure and potential overdose risks."]
Key facts at a glance
- LOINC
- 4023-8
- Short code
- Salicylates SerPl Ql
- Synonyms
- Salicylates SerPl Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- — – 50 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you’ve taken large amounts of aspirin, experienced symptoms like nausea, vomiting, ringing in the ears, or confusion—common signs of salicylate poisoning. It may also be used in cases of suspected overdose, poisoning, or if you’re taking aspirin for a specific medical reason and need monitoring.
What to Expect Before the Test
No special preparation is needed. You may have a blood sample drawn from a vein in your arm. If you’re taking aspirin regularly, let your provider know to ensure accurate results.
What the Results Mean
Salicylate levels above normal can indicate overdose or excessive intake. High levels may cause serious health risks, including damage to organs like the liver or kidneys. Your provider will interpret results in the context of your symptoms and medical history.
Common Symptoms of High Salicylate Levels
Symptoms may include tinnitus (ringing in the ears), headache, dizziness, nausea, vomiting, confusion, or difficulty breathing. Seek immediate medical attention if you experience these symptoms after taking aspirin.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Salicylate toxicity is a medical emergency, especially in children or those with kidney issues. High levels can disrupt acid-base balance, impair kidney function, and cause seizures or coma. Early detection and treatment are critical to prevent severe complications.
Short name
Salicylate Level
Frequently asked questions
How is this test different from other aspirin-related tests?
What if my test results are high?
Can I still take aspirin if I have this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy