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Salicylate concentration (serum/plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of salicate, a compound found in aspirin and some other medications, in your blood.

Quick summary

["Knowing your salicate level helps doctors monitor how your body processes certain medications."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
70216-7
Short code
Salicylates SerPl Scn-sCnc
Synonyms
Salicylates SerPl Scn-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 50 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you’ve taken high doses of aspirin or salicate-containing medications, especially in children or those with kidney issues. It can also help assess toxicity, such as from accidental overdose or improper medication use.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. If you’re on long-term salicate therapy, your doctor may advise timing the test around when you last took your medication.

What the Results Mean

Results are compared to a general reference range, but exact values can vary by lab. High levels may indicate overdose or improper metabolism, while low levels might suggest insufficient medication. Your doctor will interpret results in the context of your medical history and symptoms.

Common Causes of Abnormal Results

Elevated salicate levels can stem from intentional or accidental overdose, kidney problems, or certain liver conditions. Low levels may occur if you’re not taking your medication as prescribed or if your body rapidly processes it.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Salicylate Level

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will contact you with the final report.
Can I drink water before the test?
Yes, you can drink water as usual unless instructed otherwise by your doctor. Avoid caffeine or alcohol before the draw if your doctor specifies it.
Is there any risk or discomfort with this test?
The test involves a small needle inserted into your arm, which may cause mild discomfort or bruising. Most people feel little to no pain afterward. If you’re prone to bleeding or have a hard time with needles, let your doctor know.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy