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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood, a type of antibody that plays a role in allergic reactions.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39548-3
Short code
Salmon IgE/IgE total %
Synonyms
Salmon IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens like pollen, dust, or certain foods. While IgE is normal in small amounts, higher levels may signal an allergic reaction or immune disorder.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, rashes, or breathing difficulties that suggest allergies. It can also help diagnose conditions like hay fever, asthma, or certain parasitic infections.

How Is the Test Done?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed to measure IgE levels using immunoassay methods.

What Do Results Mean?

Results are not given in a single range but compared to your doctor’s assessment of your symptoms and medical history. Elevated IgE levels may indicate allergies or immune-related conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Elevated IgE levels often point to allergic reactions or conditions like asthma or chronic urticaria (hives). Low levels may suggest a weakened immune response to allergens, though this is less common. Always discuss results with your healthcare provider.

Short name

IgE Total

Frequently asked questions

Can IgE levels change over time?
Yes, IgE levels can fluctuate depending on exposure to allergens, underlying health conditions, or treatments like allergy immunotherapy (allergy shots). Regular monitoring may be needed if you have ongoing symptoms.
What triggers might affect my IgE test results?
Recent exposure to allergens, infections, or certain medications could temporarily alter IgE levels. Avoiding known triggers for a few days before testing may help provide more accurate results.
Do I need to prepare for this test?
No special preparation is usually needed, but inform your doctor about any medications or conditions that might affect results, such as recent infections or immune-suppressing treatments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy