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Hemoglobin A1c (HbA1c) with 24-hour urine collection for albumin-to-creatinine ratio (UACR)

Published: August 9, 2026Updated: August 16, 2026

This test measures your long-term blood sugar control (HbA1c) and checks for kidney damage by comparing albumin and creatinine in your urine over 24 hours.

Quick summary

["Helps track diabetes management and kidney health in one combined assessment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105801-5
Short code
S.anginosus grp DNA Ct Bld + Qn NAA+pr
Synonyms
S.anginosus grp DNA Ct Bld + Qn NAA+pr
Category
coagulation
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Understanding Blood Sugar Control

HbA1c reflects the average blood sugar levels over the past 2–3 months, providing insight into how well your diabetes or prediabetes is managed. It’s a key marker for long-term complications like nerve damage or heart disease.

Assessing Kidney Function and Protein Loss

The urine albumin-to-creatinine ratio (UACR) detects early kidney problems by measuring small amounts of albumin (a protein) in urine relative to creatinine (a waste product). High ratios may signal kidney strain from diabetes or other conditions.

Why This Test Matters Together

Combining these tests offers a fuller picture: HbA1c shows blood sugar trends, while UACR identifies kidney risks. Together, they help prevent serious complications like kidney failure or cardiovascular disease.

What to Expect Before the Test

For HbA1c: No special prep is needed. For UACR: Collect all urine over 24 hours in a container (morning urine discarded). Drink usual fluids but avoid diuretics (caffeine, alcohol).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: HbA1c and UACR together identify diabetes-related risks. Low HbA1c with high UACR may indicate poor glucose control masking kidney issues, while high HbA1c alone may need kidney monitoring.

Short name

HbA1c + UACR profile

Frequently asked questions

How often should I get this test?
Typically recommended annually for people with diabetes or prediabetes, but your doctor may adjust based on your health status and blood sugar levels.
What do abnormal results mean?
High HbA1c (typically ≥6.5%) suggests poor blood sugar control, while elevated UACR (typically ≥30 mg/g) may indicate kidney problems. Both require follow-up with your healthcare team.
Can diet or exercise affect these results?
Yes—HbA1c reflects long-term trends, so consistent lifestyle changes (like diet or exercise) can improve results over time. UACR may fluctuate with hydration or kidney strain from diet (e.g., high salt), so results should be interpreted with your doctor’s guidance.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy