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Serum Oxygen Saturation (SaO₂) and Blood Carbon Monoxide (CO) Analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures how well oxygen is being carried in your blood and checks for exposure to carbon monoxide, a harmful gas.

Quick summary

["Helps assess lung function and detect potential poisoning from carbon monoxide."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
28642-7
Short code
SaO2 % BldCoA
Synonyms
SaO2 % BldCoA
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test includes two key measurements: **Serum oxygen saturation (SaO₂)**, which reflects the percentage of oxygen bound to hemoglobin in your blood, and **carbon monoxide levels**, which indicate exposure to this toxic gas. Oxygen saturation is typically measured using a blood gas analysis, while carbon monoxide levels are detected through a specialized immunoassay or chemical method.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like shortness of breath, dizziness, or headache—common signs of low oxygen or carbon monoxide poisoning. It’s also used in monitoring patients with lung conditions (e.g., COPD, asthma) or those exposed to smoke or fumes.

What to Expect During the Test

A small blood sample is drawn from a vein, usually in your arm. The blood is processed to measure oxygen saturation and carbon monoxide levels. Results are typically ready within a few hours to a day, depending on lab methods.

Common Causes of Abnormal Results

Low oxygen saturation may signal lung disease, anemia, or high altitude. Elevated carbon monoxide levels often point to accidental exposure (e.g., car exhaust, fires) or intentional poisoning. Both conditions require prompt medical attention.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Oxygen & CO Blood Test

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 1–24 hours, depending on the lab’s processing speed and whether additional confirmatory tests are needed. Your doctor will discuss the timing with you before scheduling the test.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise by your doctor. Some tests may require fasting, but this test does not. Always follow your provider’s specific instructions.
Is there any risk or discomfort with this blood draw?
The blood draw is quick and may cause mild discomfort (like a pinch), but it’s over in seconds. Rarely, a bruise or slight swelling can occur at the site. If you’re on blood-thinning medication or have a clotting disorder, let your doctor know.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy