Skip to content

Serum or Plasma Oxygen Saturation (Partial Pressure)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of oxygen bound to hemoglobin in your blood, helping assess how well your lungs are delivering oxygen to your body.

Quick summary

["Evaluates lung function and oxygen delivery efficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97549-0
Short code
SaO2 % BldCV
Synonyms
SaO2 % BldCV
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

The test measures the partial pressure of oxygen in your blood, which reflects how effectively your lungs transfer oxygen from inhaled air into your bloodstream. This is typically done using a blood gas analysis, often paired with other measurements like carbon dioxide levels or pH.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like shortness of breath, fatigue, or signs of poor oxygenation (e.g., confusion, rapid heartbeat). It’s also used in monitoring conditions like chronic obstructive pulmonary disease (COPD), pneumonia, or during surgeries requiring precise oxygen management.

How Is the Test Performed?

A small blood sample is taken from a vein, usually in your arm. The sample is analyzed in a lab to measure oxygen saturation levels, often alongside other blood gas metrics like carbon dioxide or pH.

What Do the Results Mean?

Results are compared to standard ranges for healthy individuals, though exact values can vary based on factors like altitude, health conditions, or medical devices (like ventilators). Low levels may indicate lung problems, while high levels could suggest conditions like polycythemia (increased red blood cells).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low oxygen saturation (hypoxemia) can signal serious issues like lung infections, heart failure, or respiratory disorders. High saturation may reflect conditions like polycythemia or altitude exposure. This test is critical for diagnosing and managing breathing problems, guiding treatments like oxygen therapy, or assessing recovery after illness.

Short name

Oxygen Saturation (PaO₂)

Frequently asked questions

What causes low oxygen levels in this test?
Low oxygen saturation can result from lung diseases (e.g., asthma, COPD), heart problems, high altitudes, or conditions that reduce blood flow (e.g., blood clots). It may also occur during anesthesia or after certain surgeries.
How often should I expect this test?
The frequency depends on your health condition. Some patients need it weekly or monthly for chronic conditions, while others may only need it once during a routine checkup or after an acute event.
Can I prepare for this test?
No special preparation is needed, but avoid smoking or heavy exercise 1–2 hours before the test, as these can temporarily affect oxygen levels. If you’re on oxygen therapy, follow your doctor’s instructions for when to stop or adjust.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy