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Oxygen saturation in arterial blood measured from arterial blood gas (PO₂)

Published: August 9, 2026Updated: August 17, 2026

This test measures how well your blood is carrying oxygen from your lungs to the rest of your body. It’s often checked alongside blood gas results to assess lung function and oxygen levels.

Quick summary

["Helps diagnose lung issues or low oxygen levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
51731-8
Short code
SaO2 % BldV from pO2
Synonyms
SaO2 % BldV from pO2
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
80
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
calculated-from-oxygen-partial-pressure
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like shortness of breath, fatigue, or confusion, especially after conditions like pneumonia, asthma, or heart problems. It’s also used during surgeries, anesthesia, or if you have chronic lung diseases like COPD. Sometimes, it’s part of a broader blood gas evaluation to check how well your body is processing oxygen.

How the Test Works

A small sample of your blood is taken from an artery (usually in your arm) and analyzed in a lab. The test measures the percentage of oxygen molecules bound to hemoglobin in your red blood cells, which is represented as a percentage (saturation). The PO₂ value indicates the partial pressure of oxygen in your blood, which can help correlate with oxygen saturation levels.

What to Expect Before the Test

You’ll likely have a small needle inserted into your arm or wrist to draw blood. It may feel like a quick pinch, and you might feel a brief sting. If you’re having surgery or a procedure, the doctor may explain how the test fits into your care plan. Avoid eating or drinking for a short time before if instructed.

What to Expect During the Test

The blood sample is sent to a lab where it’s analyzed immediately or within minutes. Results are usually available within a few hours. If you’re undergoing continuous monitoring (like in the ICU), results may be real-time.

Reference range

NCBI: PaO2 80-100 mmHgN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Arterial Oxygen Saturation (SaO₂) from PO₂

Frequently asked questions

What does an abnormal result mean?
An abnormal result could mean your lungs aren’t working well to deliver oxygen, or your body isn’t using it properly. This might happen with lung diseases, heart problems, or even high altitudes. Your doctor will discuss the results with you and may recommend further tests or treatments.
Can I eat or drink before this test?
Check with your doctor or lab about fasting rules, but generally, you may eat or drink normally unless specified otherwise. Some tests require fasting for a few hours before drawing blood.
How long will I wait for results?
Results are typically available within a few hours for routine tests. If you’re in a hospital or clinic setting, results may be available immediately or within a few hours depending on the lab’s process.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy