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Serum or plasma concentration of bilirubin (total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. High levels may indicate liver disease, bile duct blockage, or hemolysis.

Quick summary

["Total bilirubin helps diagnose and monitor conditions affecting your liver and bile flow."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71847-8
Short code
SaO2 DF BldCoV
Synonyms
SaO2 DF BldCoV
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for liver problems, such as hepatitis, cirrhosis, or gallstones. It can also help diagnose conditions like jaundice (yellowing of the skin and eyes) or hemolytic anemia, where red blood cells break down too quickly. Sometimes, it’s used to monitor treatment progress for these conditions.

What to Expect Before the Test

You’ll typically have a small needle inserted into your arm to draw blood. No special preparation is needed, but let your provider know if you’re on blood thinners or have a history of bleeding issues.

What the Results Mean

Results are usually reported in milligrams per deciliter (mg/dL). High levels (above normal) may suggest liver disease, bile duct problems, or red blood cell breakdown. Low levels are less common but can occur with certain liver conditions or severe dehydration.

Common Conditions Linked to Bilirubin Levels

Elevated bilirubin is often linked to liver disorders (e.g., hepatitis, cirrhosis), blockages in the bile ducts, or conditions like sickle cell anemia or hemolytic diseases. Low levels may be due to liver dysfunction or other metabolic issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Bilirubin is a key marker for liver function and bile flow. High levels can signal jaundice, liver damage, or gallbladder issues, while abnormal patterns may help pinpoint the cause of symptoms like fatigue, dark urine, or pale stools.

Short name

Total bilirubin

Frequently asked questions

What causes bilirubin to rise in the blood?
Bilirubin levels can rise due to liver problems (e.g., hepatitis), blockages in the bile ducts, or conditions where red blood cells break down faster than the liver can process them (e.g., anemia, certain blood disorders).
How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab. Your provider will discuss them with you during your follow-up visit.
Can diet affect bilirubin levels?
Diet alone rarely affects bilirubin levels, but certain foods (like excessive alcohol or high-fat meals) may influence liver function indirectly. Avoiding alcohol and eating a balanced diet can support liver health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy