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Serum or plasma concentration of bilirubin (total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down.

Quick summary

["Total bilirubin helps diagnose liver and bile duct issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71846-0
Short code
SaO2 DF BldMV
Synonyms
SaO2 DF BldMV
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Bilirubin?

Bilirubin is a waste product created when your body recycles old red blood cells. Normally, it’s filtered out of your blood by your liver and excreted through bile into your intestines. When bilirubin builds up in your blood, it can cause jaundice, a condition where your skin and eyes turn yellow.

Why Might You Need This Test?

Your doctor may order this test to check for liver problems, such as hepatitis, cirrhosis, or blockages in your bile ducts. It can also help diagnose conditions like hemolytic anemia, where red blood cells break down too quickly, or certain types of cancer.

How Is the Test Done?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it’s analyzed to measure the total bilirubin level. No special preparation is usually needed, but let your doctor know if you’re taking medications that could affect results.

What Are Common Results?

Results are reported in milligrams per deciliter (mg/dL). High levels may indicate liver or bile duct problems, while very low levels are rare and often linked to rare genetic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High bilirubin levels can signal liver disease, bile duct obstructions, or red blood cell disorders. Low levels are less common but may occur in newborns (physiologic jaundice) or in conditions affecting red blood cell production. Always discuss results with your healthcare provider for personalized interpretation.

Short name

Total bilirubin

Frequently asked questions

What causes elevated bilirubin?
Elevated bilirubin can result from liver diseases (like hepatitis), bile duct blockages, or conditions that cause rapid red blood cell destruction (like certain blood disorders). It can also appear in newborns due to immature liver function.
What should I do if my bilirubin is high?
If your bilirubin is high, your doctor may recommend further tests (like liver function tests) or treatments depending on the cause. Follow their guidance closely, as managing conditions like hepatitis or gallstones may involve lifestyle changes or medications.
Can diet affect bilirubin levels?
Diet alone rarely affects bilirubin levels, but certain foods (like those high in vitamin K or fiber) may interact with medications used to treat liver conditions. Always ask your doctor or dietitian about dietary recommendations tailored to your health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy