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Serum Oxygen Saturation (Partial Pressure)

Published: August 9, 2026Updated: August 16, 2026

This test measures how much oxygen is bound to hemoglobin in your blood, often used to assess oxygen levels in arterial blood.

Quick summary

["Helps doctors check if your blood is getting enough oxygen from the lungs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8845-0
Short code
SaO2 % LV
Synonyms
SaO2 % LV
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test evaluates the partial pressure of oxygen (measured in millimeters of mercury, mmHg) bound to hemoglobin in your blood. This reflects how well oxygen is being transported from the lungs to tissues. It’s particularly useful in diagnosing conditions affecting oxygen delivery, such as respiratory disorders or anemia.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like shortness of breath, fatigue, or signs of poor oxygenation (e.g., blue lips or skin). It’s also used in monitoring patients with chronic lung diseases, heart conditions, or those undergoing treatments that could affect oxygen levels.

Common Uses

Common reasons include evaluating lung function, assessing oxygenation in critical care settings, or monitoring conditions like chronic obstructive pulmonary disease (COPD), sleep apnea, or anemia.

How the Test Works

This is typically measured directly from an arterial blood sample (whole blood) using specialized equipment that analyzes oxygen binding to hemoglobin. Unlike a standard blood draw, an arterial sample is taken from a blood vessel in your arm or wrist.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low oxygen saturation (partial pressure) may indicate respiratory failure, severe lung disease, or other conditions impairing oxygen transport. High values could suggest polycythemia (overproduction of red blood cells) or other metabolic factors. Always discuss results with your provider for personalized interpretation.

Short name

None

Frequently asked questions

What does a low oxygen saturation mean?
A low partial pressure of oxygen in your blood can signal problems like poor lung function, fluid buildup in the lungs, or conditions that prevent oxygen from being absorbed efficiently. Your provider will review symptoms and other test results to determine the cause.
How is this test different from a standard blood oxygen test (like pulse oximetry)?
This test measures the actual partial pressure of oxygen in your blood (in mmHg), while a pulse oximeter estimates oxygen saturation (SpO₂) by measuring light absorption on your finger. Both are useful but provide different insights—your provider may use both together for a full picture.
Can diet or exercise affect this test result?
Diet or exercise alone typically do not directly affect the partial pressure of oxygen in your blood. However, conditions like high altitude or certain medications (e.g., those affecting breathing) may influence results. Always follow your provider’s instructions for fasting or preparation if required.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy