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Sarcosine in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sarcosine, a naturally occurring amino acid, in your blood. Sarcosine is involved in cellular metabolism and may be studied in conditions affecting muscle, kidney function, or certain cancers.

Quick summary

["Sarcosine levels can help assess metabolic health or detect underlying conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13413-0
Short code
Sarcosine Amn-mCnc
Synonyms
Sarcosine Amn-mCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or risk factors for conditions like muscle disorders, kidney disease, or certain types of cancer. It may also be part of a broader metabolic evaluation.

What Does the Result Mean?

Results are not typically provided as a single reference range since sarcosine levels can vary based on health status, diet, and other factors. Your provider will interpret the result in the context of your medical history and other test results.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The sample is sent to a lab for analysis using a high-performance liquid chromatography (HPLC) method, which separates and measures sarcosine levels accurately.

Common Conditions Monitored

While sarcosine itself isn’t commonly monitored for routine health, elevated levels may be associated with muscle wasting, certain cancers (like prostate or bladder cancer), or metabolic disorders. Low levels might be seen in conditions affecting amino acid metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance of sarcosine testing includes its potential role in diagnosing or monitoring conditions where amino acid metabolism is disrupted. For example, elevated sarcosine has been studied in prostate cancer due to its role in tumor metabolism, though it is not a standard diagnostic test.

Short name

Sarcosine Level

Frequently asked questions

What causes sarcosine levels to change?
Changes in sarcosine levels can result from underlying medical conditions (e.g., muscle diseases, cancers), dietary factors (e.g., protein intake), or medications. Your provider will consider these factors when evaluating your results.
How long does it take to get results?
Test results are typically available within 1 to 3 business days, depending on lab processing times. Your provider will contact you once results are ready.
Can diet affect sarcosine levels?
Yes, dietary protein and certain foods may influence sarcosine levels. If you suspect diet plays a role, discuss it with your provider before or after the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy