Skip to content

SARS-CoV-2 Antibody Profile, Qualitative (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that your immune system makes in response to the SARS-CoV-2 virus, which causes COVID-19. Antibodies can help your body fight the virus and may stay in your system for months or longer after infection.

Quick summary

["Detects past or potential immunity to COVID-19 through antibody presence."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94503-0
Short code
SARS-CoV-2 Ab Pnl SerPlBld IA.rapid
Synonyms
SARS-CoV-2 Ab Pnl SerPlBld IA.rapid
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-rapid
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

This test looks for different types of antibodies that your immune system produces after exposure to SARS-CoV-2. Antibodies are proteins that help your body recognize and fight infections. The test may include detecting IgG, IgM, and other antibody classes that indicate either recent infection or long-term immunity.

Why Might You Need This Test?

Healthcare providers may order this test to determine if you’ve been exposed to COVID-19, assess immunity after vaccination, or evaluate your risk of infection in certain settings (e.g., before travel, work, or returning to school). It can also help guide decisions about future precautions.

How Is This Test Performed?

A small blood sample is drawn from a vein in your arm. The blood is then tested in a lab using an immunoassay method to detect specific antibodies. The results are qualitative, meaning they indicate whether antibodies are present or not, rather than measuring exact amounts.

What Do the Results Mean?

Positive results suggest your immune system has recognized and responded to SARS-CoV-2, which may mean you’ve had COVID-19 or have been vaccinated. Negative results mean no detectable antibodies were found at this time. Results alone do not confirm current infection; they reflect past exposure or immunity status.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Antibodies and COVID-19 Immunity

Short name

SARS-CoV-2 Antibody Screen/Confirm

Frequently asked questions

How long do antibodies stay in your system after COVID-19 or vaccination?
Antibodies may persist for months or years after infection or vaccination, but their levels can decline over time. Some antibodies may fade, while others may remain protective. Follow-up testing may be recommended if you’re at higher risk or need ongoing immunity assessment.
Can antibodies protect me from getting COVID-19 again?
Antibodies provide some protection, but they are not a guarantee against reinfection. Vaccination and other preventive measures (like masks, handwashing, and avoiding crowds) remain important for reducing your risk of COVID-19.
What if my antibody test is negative but I still feel sick?
A negative antibody test does not rule out current infection. If you have symptoms, consider getting tested for active COVID-19 using a rapid antigen test or PCR test, as these can detect the virus itself rather than antibodies.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy