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SARS-CoV-2 Antibody (Serum/Plasma) – Qualitative Immunoassay (Screen/Confirm)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that your immune system produces in response to the SARS-CoV-2 virus, which causes COVID-19. Antibodies may appear weeks after infection or vaccination.

Quick summary

["This test helps determine if your body has developed immunity to COVID-19, either from past infection or vaccination."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94769-7
Short code
SARS-CoV-2 Ab SerPl IA-aCnc
Synonyms
SARS-CoV-2 Ab SerPl IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test looks for specific antibodies (immunoglobulins) in your serum or plasma that target the SARS-CoV-2 virus. These antibodies are part of your immune response and can indicate exposure to the virus or vaccination. The test is designed to be both a screening and confirmatory tool, depending on clinical context.

Why Might You Need This Test?

Healthcare providers may recommend this test if you have had symptoms of COVID-19, have been exposed to the virus, or if you are recovering from an infection. It may also be used to assess immunity in vaccinated individuals or to monitor ongoing immunity over time.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is then tested using an immunoassay method, which detects the presence of antibodies against SARS-CoV-2. This process typically involves a laboratory analysis to identify antibody levels.

What Are the Possible Results?

Results are qualitative (positive or negative) and indicate whether antibodies were detected. A positive result suggests your immune system has recognized the virus or vaccination, while a negative result means no detectable antibodies were found at the time of testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive antibody test can confirm past infection or vaccination-induced immunity, which may provide protection against future infection. However, antibody levels can wane over time, and immunity may not be lifelong. This test is not a substitute for ongoing vaccination or other preventive measures. Clinical interpretation should always be done by a healthcare provider based on your medical history and symptoms.

Short name

SARS-CoV-2 Antibody Test

Frequently asked questions

When Should I Expect Results?
Results are usually available within a few days to a week, depending on the laboratory’s processing time. Your healthcare provider will contact you with the results and any next steps.
What Does a Positive Test Mean for Me?
A positive test means your immune system has likely encountered the virus or received a COVID-19 vaccine. This does not guarantee immunity against future infections, as antibody levels can decrease over time. Follow-up testing or vaccination may be recommended based on your healthcare provider’s guidance.
Can Antibody Levels Change Over Time?
Yes, antibody levels can decrease after infection or vaccination. Some individuals may develop lower antibody levels over months or years, which is why ongoing vaccination and monitoring may be advised, especially if you are at higher risk for severe disease.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy