SARS-CoV-2 Immunoglobulin G Antibody Titration by Enzyme-Linked Immunoassay (Serum/Plasma)

What Does This Test Measure?

The test detects IgG antibodies, which are produced by your immune system after you’ve been exposed to the virus. These antibodies are part of your body’s immune response and can last longer than other types of antibodies (like IgM). IgG antibodies indicate that your immune system has likely been exposed to the virus at some point, even if you didn’t experience symptoms or had a mild illness.

Why Might You Need This Test?

Healthcare providers may order this test to confirm past exposure to COVID-19, especially if you’ve had symptoms, received a positive test result, or are in a setting where exposure risk is high. It can also help determine if you’ve developed immunity that might protect you from future infections.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is then sent to a lab where it’s analyzed using an enzyme-linked immunoassay (ELISA) method. This test looks for IgG antibodies in your serum or plasma, which are proteins produced by your immune system in response to the virus.

What Are the Results Typically Used For?

Results can help determine if you’ve had an immune response to COVID-19, which may suggest past infection. However, IgG alone doesn’t confirm current infection—it’s usually interpreted alongside other factors, such as medical history or symptoms. This test is often used in conjunction with other diagnostic tools for guidance.