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SARS-CoV-2 IgG Antibody Detection, Serum/Plasma (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of IgG antibodies against the SARS-CoV-2 virus, which may indicate past infection with COVID-19.

Quick summary

["IgG antibodies suggest your body has developed immunity after recovering from COVID-19."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94761-4
Short code
SARS-CoV-2 IgG DBS Ql IA
Synonyms
SARS-CoV-2 IgG DBS Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG antibodies are a type of immune protein your body produces in response to a virus, like SARS-CoV-2. If you have these antibodies, it often means you’ve been exposed to the virus before and your immune system has recognized it. This test does not measure the amount of antibodies but simply whether they are present.

Why Might You Need This Test?

Healthcare providers may order this test to assess immunity after recovering from COVID-19, evaluate exposure risk in certain settings, or monitor immune response in vaccinated individuals. It’s not a diagnostic test for active infection.

What to Expect Before the Test

No special preparation is needed. A blood sample will be taken from a vein in your arm, similar to other blood tests. You may feel a slight pinch, but it usually takes a few minutes to complete.

What to Expect After the Test

After the test, you can resume normal activities. There may be some mild bruising or soreness at the injection site, but this typically goes away quickly. Avoid vigorous activity for a few hours if you experience discomfort.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

SARS-CoV-2 IgG Antibody Test

Frequently asked questions

Can this test tell me if I have immunity to COVID-19?
While positive IgG results suggest past infection and some level of immunity, they do not guarantee lifelong immunity. Immunity may vary by individual and can decline over time. Vaccination remains the best way to build and maintain protection.
What does a positive result mean?
A positive result means your blood contains IgG antibodies against SARS-CoV-2, which may indicate you’ve had COVID-19 before. This does not confirm immunity alone and should be interpreted alongside clinical judgment and vaccination status.
Can I get this test if I’ve been vaccinated?
Yes, this test can be performed after vaccination to check for IgG antibodies, though vaccination primarily triggers other immune responses (like neutralizing antibodies) that this test does not measure. Results should be discussed with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy