SARS-CoV-2 Mutational Profile in Genomic DNA (from Specimen)
This test analyzes genetic variations (mutations) in the SARS-CoV-2 virus genome, which may help identify specific viral strains or mutations associated with infection characteristics.
["This test helps determine if the virus has certain genetic changes that could affect how it behaves or responds to treatment."]
Key facts at a glance
- LOINC
- 103557-5
- Short code
- SARS-CoV-2 Mpro gene mut Spec
- Synonyms
- SARS-CoV-2 Mpro gene mut Spec
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms of COVID-19, if you’ve been exposed to the virus, or if you’re part of a study or surveillance program tracking viral mutations. It can also be used to monitor changes in the virus over time in certain clinical settings.
What the Test Measures
The test detects specific genetic mutations in the SARS-CoV-2 virus’s genome, which are small changes in the virus’s DNA sequence. These mutations can influence how the virus spreads, behaves, or interacts with treatments.
Sample Collection and Preparation
This test typically uses a sample of viral genetic material collected from respiratory specimens (e.g., nasal or throat swabs) during a COVID-19 test. The sample is processed to extract viral DNA for analysis.
What to Expect During Testing
You will likely receive a standard COVID-19 test (like a PCR or antigen test) to confirm the presence of the virus before this mutation analysis. Results are usually reported alongside the overall viral strain profile, not individual mutation details unless specifically requested.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
SARS-CoV-2 Mutation Screening
Frequently asked questions
This test helps identify specific viral strains that may have mutations linked to increased transmissibility, vaccine resistance, or altered disease severity. Understanding these mutations can guide public health responses, treatment decisions, or vaccine development strategies.
How long will it take to get results?
Can this test be done on my own at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy