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SARS-CoV-2 Nucleic Acid Test by Qualitative Probe (Qualitative RT-PCR)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the virus that causes COVID-19 to help determine if you have an active infection.

Quick summary

["Determines if COVID-19 is currently present in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94510-5
Short code
SARS-CoV-2 N gene Ct Spec Qn NAA+probe
Synonyms
SARS-CoV-2 N gene Ct Spec Qn NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a small sample of your respiratory secretions (like nasal or throat swab) to identify the virus’s genetic material. A probe detects specific sequences unique to SARS-CoV-2, confirming infection if present.

What to Expect Before the Test

You may experience mild discomfort during swab collection, but no preparation is needed. Avoid smoking or using mouthwash 15 minutes before testing to ensure accurate results.

Test Results and Interpretation

Results are typically reported as either positive (indicating active infection) or negative (no detectable virus). A negative result does not always mean you are not infected—it may take time for the virus to be detectable.

When Results May Be Important

Positive results prompt isolation measures and may guide treatment decisions, such as antiviral medications. Negative results help monitor recovery or assess exposure risk in high-risk settings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

COVID-19 Nucleic Acid Test

Frequently asked questions

Why was this test ordered?
Your healthcare provider may order this test to diagnose suspected COVID-19, screen asymptomatic individuals in high-risk groups, or monitor exposure in healthcare or community settings.
What does a positive result mean?
A positive result confirms an active SARS-CoV-2 infection and requires immediate isolation and follow-up with your provider. It does not indicate severity or immunity.
Can I get this test at home?
Some at-home tests exist, but this is typically performed in a clinical setting by a healthcare professional for accuracy and safety.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy