SARS-CoV-2 Nucleic Acid Detection by Saliva Probe (Qualitative)
This test checks for the presence of genetic material from the virus that causes COVID-19 in your saliva. It helps determine if you may have an active infection.
["A COVID-19 saliva test to check for the virus’s genetic material, often used for screening or monitoring exposure."]
Key facts at a glance
- LOINC
- 98493-0
- Short code
- SARS-CoV-2 ORF1b Sal Ql NAA+probe
- Synonyms
- SARS-CoV-2 ORF1b Sal Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- CPT
- 86430
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test uses a special probe to detect the virus’s genetic material (RNA) in your saliva. If the virus is present, the probe binds to its genetic sequence, triggering a result. This method is highly sensitive and specific for identifying active infection.
When You Might Need This Test
Your healthcare provider may recommend this test if you have symptoms of COVID-19, have been exposed to someone with the virus, or are part of a screening program (e.g., pre-exposure, workplace, or travel). It is also used to monitor recovery or check for reinfection.
Sample Collection and Preparation
You’ll provide a saliva sample using a swab or dropper. The sample is collected early in the morning for best accuracy. The lab processes the saliva to extract viral RNA before testing.
Test Results and Interpretation
Results are qualitative: positive (virus detected) or negative (virus not detected). A positive result means you may have an active infection and should follow isolation guidelines. A negative result does not rule out infection if symptoms persist or exposure was recent.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is critical for early detection of COVID-19, guiding treatment decisions, public health interventions, and reducing virus spread. It is less invasive than nasal swabs and may be preferred for comfort or accessibility in some settings.
Short name
SARS-CoV-2 RNA in Saliva (PCR Screen)
Frequently asked questions
What does a positive result mean?
Can a negative result mean I don’t have COVID-19?
How soon after exposure can I get a positive result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy