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SARS-CoV-2 Nucleic Acid Detection by Reverse Transcription Polymerase Chain Reaction (RT-PCR) with RNA Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the virus that causes COVID-19. It helps determine if you have an active infection.

Quick summary

["This test checks for COVID-19 virus presence using a simple nasal or throat swab sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105749-6
Short code
SARS-CoV-2 RNA BAL Ql NAA+probe
Synonyms
SARS-CoV-2 RNA BAL Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a special swab to collect cells from your nose or throat. These cells are then analyzed in a lab to look for the virus’s genetic material. If the virus is present, the test can detect it using a probe that binds to specific viral RNA sequences.

What to Expect Before the Test

You may need to fast or avoid certain medications before the test, depending on your healthcare provider’s instructions. Bring any medications you’re currently taking to your appointment.

What to Expect During the Test

The test is quick and painless. A healthcare provider will insert a swab into your nose or throat to collect a sample. You may feel a slight discomfort, but it usually lasts only a few seconds.

What to Expect After the Test

You can return to your normal activities immediately after the test. Avoid rinsing your mouth or nose with water for at least 15 minutes after the swab is removed to ensure accurate results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing active COVID-19 infections. Positive results indicate the presence of the virus and may require isolation, treatment, or further testing. Negative results suggest no active infection, but they do not rule out past exposure or immunity. Results guide decisions about quarantine, treatment, and public health measures.

Short name

SARS-CoV-2 RT-PCR Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on the lab’s processing time. Your healthcare provider will contact you with the results as soon as they are ready.
Can I have false-positive or false-negative results?
While rare, false results can occur due to sample contamination, improper handling, or technical issues. False negatives are more common if the test is taken too early after exposure or if symptoms are mild. Follow-up testing may be recommended if initial results are unclear.
Is this test covered by insurance?
Most insurance plans cover COVID-19 testing as medically necessary. However, coverage may vary, so check with your insurance provider or healthcare provider for details about costs and out-of-pocket expenses.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy