SARS-CoV-2 Nucleic Acid Test by Qualitative Probe (Serum/Plasma)
This test detects genetic material from the SARS-CoV-2 virus, the cause of COVID-19, using a probe-based method on a sample of your blood (serum or plasma).
["This test helps determine if you currently have an active COVID-19 infection."]
Key facts at a glance
- LOINC
- 94746-5
- Short code
- SARS-CoV-2 RNA Ct Spec Qn NAA+probe
- Synonyms
- SARS-CoV-2 RNA Ct Spec Qn NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test uses a specialized probe to identify specific genetic sequences unique to the SARS-CoV-2 virus. If the virus is present in your blood, the probe will bind to its genetic material, confirming an active infection. This method is highly sensitive and specific for detecting the virus.
Sample Collection
A blood sample is drawn from a vein, typically in your arm. The blood is then separated to obtain either serum (the liquid part after clotting) or plasma (the liquid part after centrifugation). This sample is sent to the lab for testing.
When You Might Need This Test
You may need this test if you have symptoms of COVID-19, such as fever, cough, shortness of breath, or fatigue, or if you have been exposed to someone with COVID-19. It can also be used for monitoring during recovery or in certain high-risk situations.
What to Expect During Testing
The process is quick and usually done in a healthcare setting. You may feel a slight pinch when the needle is inserted, but it typically doesn’t cause significant discomfort. The blood sample is then processed and analyzed immediately or within a short timeframe.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is crucial for diagnosing active COVID-19 infections. Positive results indicate the presence of the virus and may guide treatment decisions, such as starting antiviral medications or isolating to prevent spreading the virus. Negative results mean the virus was not detected in the sample at the time of testing, though it’s possible the infection is still present but not detectable or has already cleared.
Frequently asked questions
Why might I get this test even if I don’t have symptoms?
What does a positive result mean?
How soon after exposure can I expect a result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy