SARS-CoV-2 Nucleocapsid Protein RNA Qualitative Detection by Nucleic Acid Amplification Test (NAAT)
This test checks for the genetic material of the SARS-CoV-2 virus, which causes COVID-19, in your sample. It helps determine if you have an active infection.
["A COVID-19 test to detect the virus’s genetic material, often used for diagnosis or monitoring exposure risk."]
Key facts at a glance
- LOINC
- 96897-4
- Short code
- SARS-CoV-2 RNA Pnl OPA wash NAA+probe
- Synonyms
- SARS-CoV-2 RNA Pnl OPA wash NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test uses a special probe designed to target the nucleocapsid protein of SARS-CoV-2. When the probe binds to the virus’s genetic material in your sample, it triggers a reaction that can be detected, confirming the presence of the virus.
What to Expect Before the Test
No special preparation is needed. You may provide a nasal swab (nasopharyngeal or anterior), saliva, or other approved specimen type, depending on your healthcare provider’s instructions. Follow their guidance to ensure accurate results.
When This Test Is Used
This test is typically used to diagnose an active COVID-19 infection, screen asymptomatic individuals in high-risk settings, or monitor exposure in healthcare or community settings. It may also be used for initial screening before procedures or travel.
What the Results Mean
A positive result indicates the presence of SARS-CoV-2 genetic material, suggesting an active infection. A negative result means the virus was not detected in the sample at the time of testing, but this does not definitively rule out infection if symptoms develop later.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results prompt isolation measures and may guide treatment decisions, such as antiviral therapy or monitoring. Negative results can help guide decisions about quarantine, exposure control, or further testing if symptoms arise. This test is critical for public health tracking and reducing virus spread.
Short name
SARS-CoV-2 NAAT (Nucleic Acid Test)
Frequently asked questions
What does a positive result mean?
Can a negative result mean I don’t have COVID-19?
How soon after exposure can I get tested?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy