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SARS-CoV-2 Nucleic Acid Test (Throat Swab) – Qualitative Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the SARS-CoV-2 virus, the cause of COVID-19, using a throat swab sample.

Quick summary

["This test helps determine if you have an active COVID-19 infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101289-7
Short code
SARS-CoV-2 RNA Throat Ql NAA+n-prb
Synonyms
SARS-CoV-2 RNA Throat Ql NAA+n-prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

A healthcare provider collects a sample from the back of your throat using a swab. The swab is then tested in a lab to identify the virus’s genetic material. If the test is positive, it means the virus is present in your sample, suggesting an active infection. If negative, it means the virus was not detected in this sample at the time of testing.

What to Expect Before the Test

You may need to avoid eating or drinking for a short time before the test, depending on your healthcare provider’s instructions. Wear a mask if you have symptoms of illness, as the test involves close contact with your throat.

What to Expect After the Test

You may experience mild throat irritation or discomfort after the swab is collected. Most people do not need any special care afterward, but you can rinse your mouth with warm salt water if needed to ease any soreness.

When Results Are Available

Results are typically available within 24 hours, though some labs may take longer. Follow-up instructions from your healthcare provider will guide you on what to do based on your results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing active COVID-19 infections. Positive results indicate the presence of the virus and may guide treatment decisions, isolation recommendations, or further testing. Negative results do not always mean you are not infected—testing at the time of the sample may have missed the virus. Repeat testing may be advised if symptoms develop or exposure is suspected.

Frequently asked questions

Why was I asked to take this test?
You may have been tested for COVID-19 due to symptoms like fever, cough, or shortness of breath, exposure to someone with COVID-19, or as part of routine screening in a healthcare setting.
What does a positive result mean?
A positive result means the test detected genetic material from the SARS-CoV-2 virus in your sample. This suggests you are likely infected with COVID-19 at the time of testing. Follow your healthcare provider’s guidance on next steps, such as isolating or seeking further medical care.
Can I get a false positive or false negative result?
While rare, false results can occur due to factors like sample collection timing, viral load, or lab errors. A negative result does not always mean you are not infected—repeat testing may be needed if symptoms persist or exposure is suspected.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy