Skip to content

SARS-CoV-2 Nucleic Acid Detection in Respiratory Specimen by Probe-Based Assay

Published: August 9, 2026Updated: August 16, 2026

This test checks for the genetic material of the virus that causes COVID-19 in your respiratory sample, such as a nasal or throat swab.

Quick summary

["A positive result suggests recent infection; a negative result may mean you’re not currently infected or the test was taken too early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96094-8
Short code
SARS-CoV-2+SARSr-CoV pnl Resp NAA+probe
Synonyms
SARS-CoV-2+SARSr-CoV pnl Resp NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a specialized probe to detect the virus’s genetic material (RNA) in your sample. It’s highly sensitive and designed to identify even small amounts of the virus.

What to Expect During Testing

You’ll likely have a quick nasal or throat swab. The sample is then analyzed in a lab to check for the virus’s genetic material. Results are usually available within 24–48 hours.

When This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of COVID-19, have been exposed to someone with the virus, or are required for travel, work, or school.

What the Results Mean

A **positive** result means the test detected the virus’s genetic material, indicating an active infection. A **negative** result means the virus wasn’t detected at the time of testing, but this doesn’t always confirm you’re no longer contagious.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in diagnosing COVID-19 by confirming or ruling out infection. It helps guide treatment decisions, public health measures, and contact tracing to control the spread of the virus.

Short name

SARS-CoV-2 RT-PCR (Respiratory Probe)

Frequently asked questions

Why did my doctor order this test?
Your doctor may have recommended it due to symptoms, exposure risk, or a requirement for testing (e.g., travel, workplace, or school policies). Always discuss your specific situation with them.
What does a negative result mean?
A negative result means the test did not detect the virus’s genetic material at the time of testing. However, it’s possible you may have been infected earlier or have recovered. Follow-up testing may be advised if symptoms persist.
How long does it take to get results?
Results are typically available within 24–48 hours, depending on lab processing times. Your healthcare provider will contact you with the results once they’re ready.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy